Treatment with Parkinsonia aculeata combats insulin resistance-induced oxidative stress through the increase in PPARγ/CuZn-SOD axis expression in diet-induced obesity mice
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چکیده
منابع مشابه
Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity.
Insulin resistance is a key pathophysiological feature of metabolic syndrome. However, the initial events triggering the development of insulin resistance and its causal relations with dysregulation of glucose and fatty acids metabolism remain unclear. We investigated biological pathways that have the potential to induce insulin resistance in mice fed a high-fat diet (HFD). We demonstrate that ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biochemistry
سال: 2016
ISSN: 0300-8177,1573-4919
DOI: 10.1007/s11010-016-2753-7